Endocrine Abstracts

An increasing interest in improving the quality of life of patients with autoimmune thyroid disorders has been noted during recent years. Although there is little scientific evidence, many patient-oriented publications, websites and support groups recommend changes in diet as well as nutritional supplement use as a cure for thyroid disease and the mean for ailments reduction. The presented survey aimed to explore the patients’ and medical professionals’ approach to n...

Introduction: Acromegaly is a disease associated with increased secretion of growth hormone and subsequent growth of bones, soft tissues and internal organs. An important factor influencing therapeutic treatment in recent years is the patient’s quality of life associated with the disease. In patients with acromegaly, it is significantly affected by the occurrence of depression and anxiety - agents undergoing treatment, which, however, still appear undiagnosed.<p class...

Introduction: VitD deficiency, the pandemics of which we currently observe, may result in secondary hyperparathyroidism even if not accompanied by hypocalcaemia.Aim: To assess VitD levels as a cause of secondary hyperparathyroidism.Material and methods: 257 healthy volunteers with normal kidney function (GFR< 60 ml/min) (28.4% males), median age 57 years, were included. In each participant, serum calcium, phosphates, creatinine...

Objective: Among women over 40 the prevalence of goiter in Poland is over 40% and the prevalence of vitamin D deficiency is over 80%. There have not been any previous studies that investigate the vitamin D level in women with and without goiter.Methods: 152 women-96 with and 56 without nontoxic goiter were examined in 2014. In US examination we calculated the volume of the thyroid gland and volume of nodules. Blood samples for 25-(OH) D total were taken....

: The observed increase in the incidence of Hashimoto’s thyroiditis (HT) requires research on factors that may affect its development. One of them may be vitamin D deficiency which is an epidemiological problem all over the world.Aim: The assessment of influence vitamin D deficiency on the HT activity.Material and methods: 310 people were enrolled in the study: 155 patients with HT (a-TPO and/or a-TG positivity)-144 women (93%...

52 years old man medicated with amiodaron 12 months, with laboratory confirmed hyperthyroidism, in us-examination 45 ml Basedow goiter, TRAb positive; ventricular tachycardia 180/min intermittent with sinusal tachycardia 120/min, thiamasol 120 mg i.v./daily, hydrocortisone 400 i.v. daily, crystalloids, beta blockers, diazepam, albumin. J131 scintigraphy – no iodine uptake. natriumperchlorate 1500 mg daily initially, continued next month 900 mg coused iodine uptake 17%. Fi...

Classical form of congenital adrenal hyperplasia (CAH) is associated with the impairment of enzymes involved in process of adrenal steroidogenesis. More than 90% of CAH cases are connected with mutations in the 21-hydroxylase gene CYP21A2 in the HLA class III area on the short arm of chromosome 6p21.3. CAH is characterized by a strong correlation between the genotype and the phenotype. Mutations in the CYP21A2 gene can cause different degrees of loss of 21-hy...

Introduction: Adrenal incidentaloma is an adrenal mass found on imaging studies done for other reason than suspected adrenal disease. The majority of them are non-functioning adenomas, however pheochromocytomas could be also observed. Currently, in diagnosis of incidentalomas, the assessment of hormones of adrenal cortex and medulla is performed. The aim of the study was to assess the incidence of pheochromocytoma in patients with incidentaloma.Methods: ...

Introduction: It has been shown that thyroid cancer has a significant correlation with cancers originated from other organs. The aim of this study was to investigate the association between synchronous primary cancers in patients with thyroid cancer.Material and Method: A retrospective analysis of medical records of 560 thyroid cancer patients treated in the years 2007–2013 and followed up over 2–8 years, was performed. In 38 patients (6.7%), 5...

The increase in thyroid disease frequency has been observed recently. It may be attributed to the changing iodine status, endocrine disruptors, as well as better availability of ultrasound and laboratory tests. The aim of the study was to assess the occurrence of newly recognized thyroid diseases during long-term follow-up.Material and methods: Study was carried out in 2010–2012 in Krakow area. It included 266 patients aged 23–81 years (168 fem...